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Dr. Prasanth Ragavhan
Dr. Raghavan aus Kerala in Indien Er ist Spezialist für die ayurvedischen Behandlung von Multiple Sklerose sowie weiterer chronischer Autoimmunerkrankungen. Bitte kontaktieren Sie mich, wenn Sie einen Termin wünschen oder Rückfragen haben zu einer MS-Behanndlung.http://www.ayushprana.com
Grafik und Webdesign
Diese Homepage meiner Praxis wurde erstellt von Frank Lewecke, Künstler und Webdesigner.http://www.lewecke.com
Die buddhistische Ngakpa-Gemeinschaft
Das deutsche Nyernga Ngakde-Zentrum, 2001 gegründet von Ugyen Rinpoche. Ugyen Rinpoche ist ein Lama aus der Ngakpa Tradition von Amdo, einer alten nicht-klösterlichen Tradition innerhalb des Vajrayana Buddhismus.Unsere Regionalgruppe Mittfranken läd Sie herzlich ein, Kontakt aufzunehmen und sich über den buddhistischen Lebensweg zu informieren.http://www.ngakde.org
Ein Erfahrungsbericht von Dr. Prashant über Multiple Sklerose und Neuromyelitis Optica
NEUROMYELITIS OPTICA (NMO) AND MULTIPLE SCLEROSIS (MS)Ein Artikel
von Dr. Prashnat Ragahvan - Ayush Prana Hospital India
One of the challenges the patients as well as the physicians face during the diagnosis of a demyelinating disease like MS is to differentiate MS with NMO. Till the last one year we were not equipped enough to test NMO antibody (NMO/IgG). NMO is highly prevalent in Indian sub continent. So this article is worth reading for MS patients. Here I am trying to observe some facts on both these disorders and their treatment approach in Ayush Prana.
DIFFERENCES OF NMO and MS.
NMO is presenting with optic neuritis/ visual disturbances in the initial relapses. MS may or may not have vision disturbance as an initial symptom.
MRI shows continuous spinal lesions in 3 or more vertebral body spaces whereas in MS it can be cerebrospinal form but continuous presence of lesion in spine is unlikely. Even if it is present these lesions in the spine are present more in the periphery whereas the NMO lesions are centrally located. However the currently taken MRI did not show a cross sectional picture of the cervical spine either.
NMO is fast progressing and symptoms are more severe in NMO attack than in MS attack.
NMO worsens rapidly to a state that the patient may be paraplegic and MS is mostly gradual in progression.
NMO patient will be having vomiting as a symptom, which may last for several weeks.
Immunosuppressant medicines like beta-interferon can actually worsen NMO. Incidence is more in women. It is more prevalent in Asians, Africans and Native Americans.
In NMO the immune system recognize Aquaporins-4 as foreign and develop antibodies NMO/IgG to attack these cells. Presence of NMO/IgG is confirming NMO but its accuracy is only 70%.
NMO is seldom having a secondary progressive state, Relapsing Remitting Multiple Sclerosis is having secondary progressive state even though both present a relapse and remission form.
The diagnosis of NMO is sometimes mistaken, especially among Indian patients. There are instances where continuous spinal lesions are seen in MS.
SIMILARITIES OF NMO AND MS.
Both these diseases are seen in young adults, presenting with relapse and remission form. Optic neuritis is also seen in both the diseases.
Both are affecting the Central Nervous System.
Both are considered as auto-immune disorders; pathology of demyelination is similar in both the diseases. An expert neurologist or radiologist is required to differentiate NMO & MS. Approximately 25%of the patient diagnosed with MS in East and South-East Asia are actually having NMO.
Infections can worsen both the condition. There are similarities in symptoms like optic neuritis, bladder abnormalities, sensitivity disturbances, pain etc.
WHY IT IS DIFFICULT TO DIFFERENTIATE NMO & MS?
Both are presenting with similar symptoms. The diagnostic MRI might be presenting with similar findings, only detailed study on MRI can reveal NMO. NMO antibodies are seen only in 70% of NMO patients.
In our clinical practice, the patients from India are often having continuous spinal lesions and there had been situations that NMO is misdiagnosed as MS by neurologist or radiologist. Earlier the tests for NMO antibodies were not available in India, they were sending the blood samples to Europe for the analysis. Even in NIMHANS, Banglore it started recently. It is mandatory that the patient has to get a confirmatory diagnosis before starting the treatment. We are relying on MRI and CSF findings (NMO antibodies). However a NMO negative MS patient who is having confluent cervical lesion carry a risk of fast progression with debilitating motor symptoms.
TREATMENT FOR NMO.
NMO requires treatments for longer duration and stronger medications. The duration advised is over 150 days. Normally for milder forms of MS the advised period of treatment is 60 days for 3 consecutive years, but NMO requires multiple years of treatment. In NMO, special treatment and medicines are given to stabilize the immune system what is responsible for fast progression of the disease.
MS is challenging to treat but NMO is still taking further effort in stabilizing and improving. More researches are required to find better combination of herbs. As all combinations of herbs what we take are closer to the best. A perfect herbal combination is made only from Gods hands. And there is no perfect combination and that is the thrill in treating one of the most difficult diseases on planet earth.